How a 4-Week Human Clinical Trial Study Helped Jigsaw MagSoothe® Back Its Promises With Oura Ring Data
Overview
- Company: Jigsaw Health
- Industry: Nutritional Supplements
- Product Category: Magnesium supplement
- Target Market: Adults seeking natural support for sleep, stress, and magnesium deficiency
- Study Partner: OvationLab and Heads Up Health (data aggregation and analysis)
The Challenge
But in a competitive supplement market, claims about sleep and wellness benefits require solid evidence. Consumers, practitioners, and retailers demand real-world proof, especially for interconnected issues like poor sleep and subclinical deficiencies tracked via wearables.
How do you demonstrate that a daily packet can deliver measurable improvements in sleep quality and related outcomes for people already monitoring their health?
Objective
Study Design
Participants:
65 adults with persistent poor sleep quality
Inclusion Criteria:
- Self-reported interest in improving sleep quality
- Self-reported sleep quality of average or worse
- ≥4 weeks of existing Oura Ring data with Heads Up
- Any combination of: average sleep score <75 OR readiness score <75 OR sleep efficiency <75 OR deep sleep <30 min OR REM sleep <30 min
Exclusion Criteria:
Current magnesium supplement use, obstructive sleep apnea diagnosis, prescription sleep medication use, insomnia diagnosis, pregnancy or intent to become pregnant in next 3 months, undergoing chemotherapy or cancer treatment, other chronic conditions contraindicated with supplement.
Intervention:
Daily supplementation with one packet of Jigsaw MagSoothe for 4 weeks
Data Collection:
- Validated Questionnaires (PROMIS Sleep Disturbance – 6a, Perceived Stress Scale – 4, Magnesium Deficiency Questionnaire [MDQ-10]) at baseline and end
- Oura Ring metrics (total sleep time, deep sleep, REM sleep, sleep efficiency, sleep score, HRV, resting heart rate, respiratory rate, temperature deviation) throughout
- Adverse events, product satisfaction, willingness to purchase, and open-ended feedback at end
Results That Matter
Patrick Sullivan Jr.
CEO & Co-founder of Jigsaw Health.
“The data confirmed what we’d been hearing from customers: people feel more rested,
less stressed, and magnesium-replete with MagSoothe, and now we have the numbers to
back it up.”
Key Stats at a Glance📊
| Metric | Result |
| PROMIS – Sleep Disturbance | -10.1 pts (~17%) (p<0.0001) |
| Perceived Stress Scale | -2.4 pts (~34%) (p<0.0001) |
| Magnesium Deficiency Questionnaire | -1.5 pts (~24%) (p=0.023) |
| Oura: Total sleep | +12 min (7.9 → 8.1 hrs, p=0.0021) |
| Oura: Sleep score | +1.3 pts (p=0.011) |
| Oura: Respiratory rate | – 0.3 bpm (p=0.019) |
| Completion Rate | 89.2% (Oura), 86.2% (questionnaires) |
| Serious Adverse Events | 0 |
| Satisfied or Very Satisfied Users | Median 85/100 |
| Likely to Purchase | 82% |
Changes in Validated Questionnaire* Scores following MagSoothe Supplementation (n=56)
| Baseline | End of Study | Difference | p value | |
| PROMIS – Sleep Disturbance – 6a | 59.6 | 49.5 | -10.1 | <0.0001 |
| Perceived Stress Scale – 4 | 7.1 | 4.7 | -2.4 | <0.0001 |
| Magnesium Deficiency Questionnaire – 10 | 6.3 | 4.8 | -1.5 | 0.023 |
* Lower scores indicate better health for PROMIS – Sleep Disturbance, Perceived Stress
Scale, and Magnesium Deficiency
Changes in Oura Scores following MagSoothe Supplementation (n=58)
| Baseline | End of Study | Difference | p value | |
| Total Sleep (hours) | 7.9 | 8.1 | +0.2 | 0.0021 |
| Deep Sleep (minutes) | 57.8 | 59.5 | +1.7 | 0.19 |
| REM Sleep (minutes) | 78.7 | 80.9 | +2.2 | 0.052 |
| Sleep Efficiency | 82.3 | 82.4 | +0.1 | 0.59 |
| Sleep Latency (minutes) | 16.3 | 17.7 | +1.4 | 0.022 |
| Sleep Score | 71.4 | 72.7 | +1.3 | 0.011 |
| Heart Rate Variability (HRV) | 32.7 | 34.2 | +1.5 | 0.16 |
| Resting Heart Rate (RHR) | 65.9 | 65.6 | −0.3 | 0.61 |
| Temperature Deviation (°C) | −0.01 | 0.02 | +0.03 | 0.058 |
| Respiratory Rate (bpm) | 15.5 | 15.3 | −0.1 | 0.019 |
| Readiness Score | 75.0 | 75.8 | +0.8 | 0.26 |
Safe, Passive, and Easy to Use
- No serious adverse events
- Only 8.7% mild GI discomfort
- 82% of participants said they would purchase MagSoothe again
What This Means for Consumers and Providers
For Individuals:
- No pills or complex routines, just a nightly packet
- Address sleep, stress, and magnesium issues naturally
- A data-backed way to optimize wellness with wearable insights
For Providers:
- Evidence-based supplement to recommend for sleep and deficiency support
- Clinically validated outcomes without pharmaceutical interventions
- High compliance and safety make it ideal for integrative care
What’s Next for Jigsaw MagSoothe®
With this study completed, Jigsaw MagSoothe® is positioned to:
- Launch new consumer education campaigns around validated sleep and stress
benefits - Collaborate with wellness clinics offering magnesium-focused protocols
- Enter retail and affiliate partnerships with clinical credibility to support claims
- Continue generating evidence and case studies using the Heads Up platform
Conclusion
The Jigsaw MagSoothe study is a powerful example of how nutritional interventions —sleep quality, stress relief, and magnesium repletion can be scientifically validated using consumer-grade wearables and real-world evidence tools.
Through Heads Up Health in collaboration with OvationLab, Jigsaw Health now has the data to stand behind its claims, open new markets, and build deeper trust with health-conscious consumers.
Better sleep. Less stress. Magnesium restored. All in 4 weeks. No hassle. No side effects. Just science.
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